Skip to Content
Fibromyalgia is a common syndrome in which a person has long-term pain, spread throughout the body. The pain is most often linked to fatigue, sleep problems, headaches, depression, and anxiety.
People with fibromalgia may also have tenderness in the joints, muscles, tendons, and other soft tissues.
The cause is unknown. Possible causes or triggers of fibromyalgia include:
Fibromyalgia is most common among women age 20 to 50.
The following conditions may be seen with fibromyalgia or have similar symptoms:
Pain is the main symptom of fibromyalgia. It may be mild to severe.
People with fibromyalgia tend to wake up with body aches and stiffness. For some people, pain improves during the day and gets worse at night. Some people have pain all day long.
Pain may get worse with activity, cold or damp weather, anxiety, and stress.
Fatigue, depressed mood, and sleep problems occur in almost all people with fibromyalgia. Many people say that they cannot get to sleep or stay asleep, and they feel tired when they wake up.
Other symptoms of fibromyalgia may include:
To be diagnosed with fibromyalgia, you must have had at least 3 months of widespread pain with one or more of the following:
It is no longer necessary to find tender points during the exam to make a diagnosis.
Results from blood and urine tests are normal most of the time. However, these tests may be done to rule out other conditions with similar symptoms.
The goals of treatment are to help relieve pain and other symptoms, and to help a person cope with the symptoms.
The first type of treatment may involve:
If these treatments do not work, your doctor may prescribe an antidepressant or muscle relaxant.
Other drugs are also used to treat the condition, such as:
Cognitive-behavioral therapy is an important part of treatment. This therapy helps you learn how to:
Support groups may also be helpful.
Things you can do to help take care of yourself include:
Your doctor may refer you to a pain clinic if your condition is severe.
Fibromyalgia is a long-term disorder. Sometimes, the symptoms improve. Other times, the pain may get worse and continue for months or years.
Call your health care provider if you have symptoms of fibromyalgia.
There is no known prevention.
Bennett RM. Fibromyalgia, chronic fatigue syndrome, and myofascial pain In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 274.
Clauw DJ, Arnold LM, McCarberg BH, FibroCollaborative. The science of fibromyalgia. Mayo Clin Proc. 2011;86(9):907-11.
Häuser W, Bernardy K, Ãœceyler N, Sommer C. Treatment of fibromyalgia syndrome with antidepressants. JAMA. 2009;301:198-209. PMID: 19141768 www.ncbi.nlm.nih.gov/pubmed/19141768.
McBeth J, Prescott G, Scotland G, Lovell K, Keeley P, Hannaford P, et al. Cognitive behavior therapy, exercise, or both for treating chronic widespread pain. Arch Intern Med. 2012(1);48-57. PMID: 22082706 www.ncbi.nlm.nih.gov/pubmed/22082706.
Wolfe F, Clauw DJ, Fitzcharles MA, et al. Fibromyalgia criteria and severity scales for clinical and epidemiological studies: a modification of the ACR Preliminary Diagnostic Criteria for Fibromyalgia. J Rheumatol. 2011; 38:1113. PMID: 21285161 www.ncbi.nlm.nih.gov/pubmed/21285161.
Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Katz RS, Mease P, et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res. 2010;62(5):600-610. PMID: 20461783 www.ncbi.nlm.nih.gov/pubmed/20461783.
Wolfe F, Rasker JJ. Fibromyalgia. In: Firestein GS, Budd RC, Gabriel SE, et al, eds. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 52.
Reviewed By: Gordon A. Starkebaum, MD, Professor of Medicine, Division of Rheumatology, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.